TORONTO, Jan. 23 (UPI) -- Canadian researchers have discovered a dopamine signaling complex in the brain that might lead to a new treatment for schizophrenia.
The team, lead by Drs. Susan George and Brian O'Dowd of the Center for Addiction and Mental Health, said the complex is composed of two different types of dopamine receptors that might offer a new in understanding of schizophrenia.
"This distinct unit provides a novel signaling pathway through which dopamine can impact the function of brain cells," said George. "This is significant because signaling through calcium release is a major mechanism regulating many important functions in the brain and we have provided the first direct mechanism by which dopamine can activate a calcium signal."
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